Posts filed under ‘Centers of Research Excellence’
Georgia Health Sciences University researchers are looking at blood levels of a protein (interleukin-1 receptor antagonist or IL-1ra) in children to see if decreases in its levels can be used to identify children who will develop type 1 diabetes. The children are part of the TEDDY study, a 15-year, international study of children who carry genes that put them at risk for the disease.
If IL-1ra, which helps control inflammation, pans out as a predictive tool, researchers then want to study the use of IL-1 inhibitors to prevent the disease, according to Dr. Jin-Xiong She, Director of the GHSU Center for Biotechnology and Genomic Medicine and a GRA Eminent Scholar. Read more>
Researchers from the Georgia Tech Broadband Institute demonstrated their research on Future Television as part of the international pavilion during the recent National Association of Broadcasters annual conference in Las Vegas.
Projects demonstrated at the event, which drew 90,000 attendees and exhibitors, focused on maximizing the efficiency of 3DTV, an advanced secondary screen remote control using iPhone and iPad platforms, and facilitating Hierarchical Hole Filling in 2D-with-Depth streams.
Directed by Georgia Research Alliance Eminent Scholar Nikil Jayant, the Georgia Tech Broadband Institute is an industry-guided research center addressing the convergences of broadband technologies and rich media services.
Hand and vascularized composite transplant experts from around the world will gather in Atlanta April 7-9 for the 10th Meeting of the International Hand and Composite Tissue Allotransplantation Society. The scientific meeting will include professionals involved in all aspects of donor hand and vascularized composite transplants, from the laboratory to patient care.
“This congress will be a unique venue for scientific exchange and discussion as well as an exceptional opportunity to establish, maintain and develop relationships with leaders in this multidisciplinary field,” says Linda Cendales, MD, local program organizing committee chair of the conference and director of the Emory University-Veterans Affairs Vascularized Composite Allograft Program.
On March 12 this year, Dr. Cendales was a member of the surgical team from Emory University Hospital who successfully performed a rare complete hand transplant on a 21-year-old college student. The 19-hour surgery involved two teams of surgeons, anesthesiologists, nurses, and operating room staff — one dedicated to the patient and the other to the donor arm. GRA Eminent Scholar Allan Kirk (Transplant Immunology, Emory University) was also a member of the surgical team. Read more > or See news conference >
Pediatric Nanomedicine Center joins 13 others as part of the Emory-Children’s Pediatric Research Center
Combining the medical expertise of Emory with the engineering focus of Georgia Tech and the clinical skills of Children’s Healthcare of Atlanta physicians, the new Center for Pediatric Nanomedicine (CPN) will develop targeted, molecular-sized nanoparticles as a unique approach to treating pediatric diseases. CPN is the first of its kind in the world and will focus on pediatric heart disease and thrombosis, infectious diseases, cancer, sickle cell and cystic fibrosis.
“Because nano-scale structures are compatible in size to biomolecules, nanomedicine provides unprecedented opportunities for achieving better control of biological processes and drastic improvements in disease detection, therapy and prevention,” according to Gang Bao, Ph.D., the center’s director. Bao is the Robert A. Milton Professor of Biomedical Engineering in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. Read more >
CPN is one of 14 centers and 11 core facilities that make up the multi-faceted Emory-Children’s Pediatric Research Center, a partnership of Emory, Georgia Tech, Children’s Healthcare of Atlanta, Morehouse School of Medicine and the Georgia Research Alliance.
For the second year in a row, Suniva, Inc., a GRA VentureLab company, made the Wall Street Journal’s list of the Top 50 Venture-Backed Companies. To be eligible for the ranking, companies must have received an equity round of financing in the past three years and be valued at less than $1 billion.
Based in metro-Atlanta, Suniva manufactures high-efficiency monocrystalline silicon solar cells and high-powered solar modules, which consist of Suniva’s core cell technology.
According to the company’s webstie, Suniva is producing the world’s lowest cost, highest cell conversion efficiency commercially available. Suniva is also the only high-efficiency, low-cost silicon cell manufacturer in America, with exports of more than 80% of its production to Europe and Asia.
Suniva evolved from the work of Professor Ajeet Rohatgi of the Georgia Institute of Technology’s University Center of Excellence in Photovoltaics (UCEP). A U.S. Department of Energy Center of Excellence since 1992, UCEP has distinguished itself as the premier site for silicon PV research in the U.S., bringing a unique approach of uniting cell modeling, device design, process optimization and materials analysis and characterization.
The Georgia Research Alliance invests in cutting-edge research tools at its partner universities to drive innovative research and development. These laboratory discoveries, in turn, often become the platforms on which new companies are created.
Today, two of those investments — advanced cryo-electron microscopes — were unveiled at Emory University.
One of the microscopes, equipped with phase plate technology, is one of only two such instruments in the United States and just a few in the world. Both instruments use cryo-imaging, which offers layer-by-layer views of a frozen specimen, providing ultra-high-resolution.
The instruments will be located at the Robert P. Apkarian Integrated Electron Microscopy Core (located in Emerson Hall), under the supervision of core director Elizabeth R. Wright, PhD, assistant professor of pediatrics at Emory University School of Medicine and a Georgia Research Alliance Distinguished Investigator.
“We are excited about establishing Emory as a center for cryo-electron microscopy and looking forward to making these resources available to investigators at Emory and within the region,” Wright says.
From Emory Health Sciences News
Virus-Mimicking Nanoparticles Can Stimulate Long Lasting Immunity
ATLANTA–Vaccine scientists say their “Holy Grail” is to stimulate immunity that lasts for a lifetime. Live viral vaccines such as the smallpox or yellow fever vaccines provide immune protection that lasts several decades, but despite their success, scientists have remained in the dark as to how they induce such long lasting immunity.
Scientists at the Emory Vaccine Center have designed tiny nanoparticles that resemble viruses in size and immunological composition and that induce lifelong immunity in mice. They designed the particles to mimic the immune-stimulating effects of one of the most successful vaccines ever developed – the yellow fever vaccine. The particles, made of biodegradable polymers, have components that activate two different parts of the innate immune system and can be used interchangeably with material from many different bacteria or viruses.
The results are described in this week’s issue of Nature.
“These results address a long-standing puzzle in vaccinology: how do successful vaccines induce long lasting immunity?” says senior author Bali Pulendran, PhD, Charles Howard Candler professor of pathology and laboratory medicine at Emory University School of Medicine and a researcher at Yerkes National Primate Research Center.
“These particles could provide an instant way to stretch scarce supplies when access to viral material is limited, such as pandemic flu or during an emerging infection. In addition, there are many diseases, such as HIV, malaria, tuberculosis and dengue, that still lack effective vaccines, where we anticipate that this type of immunity enhancer could play a role.”
The Emory Vaccine Center, established in 1996, is a GRA Center of Research Excellence and is directed by GRA Eminent Scholar Rafi Ahmed.